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Personal Care
To discover our scientifically proven high-efficiency product lines

Epi-On™

Patented active for skin recovery and anti-dandruff

  • Azelamidopropyl Dimethyl Amine (and) Water (and) Butylene Glycol
  • Epi-On™ is a new patented active which aims to accelerate skin recovery speed, strengthen the skin barrier, and promote epithelial formation in the weakened and damaged human skin through epigenetic regulation. It is a safe and non-irritating cosmetic ingredient for advanced skincare products to help restore skin homeostasis.

    Epi-On™ also prevents the appearance of dandruff through reducing excessive sebum secretion, inhibiting Malassezia spp. proliferation and anti-inflammation. It is safe and non-irritating cosmetic ingredient for anti-dandruff treatment to help restore scalp homeostasis.

Benefits
  • New and patented active ingredient
  • Accelerate skin repair
  • Increase cell migration
  • Promote growth factor secretion
  • Stimulate neo-epidermis formation
  • Lower 5-alpha reductase
  • Anti-Inflammation
  • Anti-bacterial
  • Safe, potent and stable
  • Non-irritating to skin
  • Non-comedogenic
Efficacy

In vitro

  • Regulation of growth factor and inflammatory related genes
  • Inhibition of inflammatory factors
  • Decrease HDAC activity
  • Increase HAT activity on epigenetic marker H4K16ac expression
  • Upregulate growth factors production
  • Cell migration promotion
  • Decrease lipid droplet in sebocytes
  • Lower 5-alpha reductase
  • Inhibition of Malassezia spp.

Ex vivo / In vivo

  • 2% and 4% Epi-On™ promotes the thickening of stratum corneum
  • 2% and 4% Epi-On™ significantly accelerates skin wound healing in just 3 days
  • 4% Epi-On™ significantly increases fibronectin protein expression on Day 3
  • 4% Epi-On™ significantly increases intefrin beta 4 expression on Day 10
  • 2% and 4% Epi-On™ reduces erythema of the lesions immediately after laser treatment
  • 2% Epi-On™ reduces erythema of the lesions at Day 2 and Day 5 after laser treatment on both normal and sensitive skin
  • 4% Epi-On™ serum effectively reduces sebum production, inhibit inflammation and decrease dandruff on scalp
Product General Information

Appearance

Pale yellow liquid

Solubility

Water soluble

Use Level

1-4%

Safety Information
  • No skin irritation
  • Non mutagenetic
  • Non pro-mutagenic
  • Insignificant-cytotoxicity